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Yusuf Kamais a major protagonist in Fantastic Beasts: The Crimes of Grindelwald. He was the son of Laurena Lestrange and Mustafa Kama and half-brother He was under an unbreakable Vow, where he swore to avenge his father and mother by killing the person Corvus Lestrange loved the most, whom he believed to be his sister Leta until learning she had a younger brother, also known as Corvus and believed to be Credence Barebone, until Leta revealed her brother was killed during the sinking of the ship Leta and Credence was on.

Later, Yusuf joined Newt Scamander, Porpentina Goldstein, Nagini, and Jacob Kowalski's side in their fight against Grindelwald, desiring to avenge Leta, who had been killed by Grindelwald.

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