The Runaways are a team of teenagers who banded together with the purpose of taking down PRIDE, a group formed by their respective parents. After witnessing them sacrifice Destiny Gonzalez, the kids made it their mission to thwart their parents' project. However, the Runaways were forced to run as they had been framed for the death of Gonzalez.
In spite of the difficulties of living in the street, the Runaways managed to find a shelter in the Hostel. They also had to deal with the arrival of Topher. The Runaways eventually teamed up with PRIDE to prevent Jonah from launching his spaceship, saving California. New ordeals arose with the LAPD strike team on PRIDE's payroll posed on them. Chase Stein elected to leave the team and to return home, joining PRIDE in the process. The Runaways were attacked by PRIDE to be forced to come home as well, which resulted in the capture of Gert Yorkes and Karolina Dean, leaving only Alex Wilder, Nico Minoru and Molly Hernandez free from PRIDE.