The relationships of Hermione Granger throughout the Harry Potter franchise.
Crookshanks

- Ron Weasley: "Hermione, that thing nearly scalped me!"
- Hermione: "He didn't mean to, did you, Crookshanks?... Poor Crookshanks, that witch said he'd been in there for ages; no one wanted him."
- Ron Weasley: "I wonder why."
- ―Ron and Hermione when she bought Crookshanks
Crookshanks was Hermione's large, bandy-legged, half-Kneazle, ginger-coloured pet cat since she bought him from the Magical Menagerie in Diagon Alley, in 1993. Nobody wanted to buy him so she did. However Ron hated the cat, especially since he continued chasing around Scabbers (in reality he was helping Sirius catch the rat, who was really his friend and the Potter family traitor Peter Pettigrew). When Scabbers went missing. Ron became with upset with Hermione because he thought her cat ate him, but Hermione was quick to defend her pet. She was proud of his cleverness once the truth got out. The latter proved to be quite true during the 1993–1994 school year.
Crookshanks recognised that Hermione had left him at The Burrow before Bill and Fleur's wedding in 1997, most likely had been left in care of Mrs Weasley or Ginny, but it is possible that they were reunited after the Second War given the deep care and affection they had for each other.
Romances
Victor Krum

Hermione with Viktor Krum.
Date; 1994
The fourth novel and film hint he and Hermione mutually liked one another. Hermione would sometimes glance at him far away, and Viktor would return the favor. Viktor later asked her to the Yule Ball hosted at Hogwarts Castle, and Hermione accepted the invitation, despite her support for Harry during the Triwizard Tournament. During the Yule Ball, Hermione and Viktor had a great time, causing Ron to grow insanely jealous. They rarely talked during the party, with Hermione finding this awkward, but having a fun time nonetheless. During the second task, Hermione was one of the hostages that Viktor had to rescue from the mermaids of the Black Lake, which he successfully completed. Shortly before the third and final task, Viktor heard the rumors of Hermione and Harry having a romantic relationship, especially after reading about it in the tabloids. However, Harry had to clarify that his and Hermione's relationship was strictly platonic, showing his support for Viktor and Hermione's relationship.
At the end of the fourth novel, Viktor gave Hermione his number, asking her to visit him in Bulgaria in the summer. The relationship was never serious, Hermione and Viktor remained in contact via exchanging letters, deciding they were better off as friends. Hermione and Viktor were reunited during the Second Wizarding War, where they met at Fleur's and Bill's wedding. The latter was a little disappointed when he saw Hermione was already in a relationship with Ron
Ron Weasley

Hermione and Ron as kids
Husband; 1991-Present
- “Oh, maybe she and Ron will be alright with a bit of counselling, you know. I wonder what happens at wizard marriage counselling? They'll probably be fine. He needs to work on his self-esteem issues and she needs to work on being a little less critical.”
- ―JK Rowling on their romatnic relationship as adults
Hermione first met Ron on the Hogwarts Express during their first year. She was extremely hurt by Ron when he insulted her about having no friends and defined her as a "nightmare," and spent the whole afternoon in the bathroom crying. He and Ron later saved her life that evening from a mountain troll. The aftermath caused them to become friends, and Ron and Hermione often had playfuly bantered each other, shown when they are studying for their finals. Of course, As they got older, Hermione and Ron would develop romantic relationships with each other.
During their second year, Ron was deeply annoyed by Hermione’s crush on Gilderoy Lockhart, indicating he may have had a crush on her even then. He also made fun of her when she accidentally consumed cat hair in her Polyjuice Potion. However, Ron was immensely saddened when Hermione was an unfortunate victim of the Basilisk and was relieved to see her alright. Though the two wanted to hug each other, they just resorted to a handshake, where Ron welcomed her back warmly. Later, in the Prisoner of Azkaban, Hermione and Ron encountered each other in Leaky Cauldron, fighting about Crookshanks chasing Scabbers (who was in reality, Peter Pettigrew). This worsened over Christmas, Ron accused Hermione's cat of eating Scabbers. Their relationship was further strained when she told McGonagall about the broom sent to Harry by an anonymous person. The boys grew mad at Hermione and ignored her for several weeks, until Hagird told them how petty they were acting. After their reconciliation, Ron helped Hermione with buckbeak's trial and was the only one to stand up for her when Snape insulted her and called Hermione an "insufferable know-it-all."
In the fourth book, it is hinted further that Ron has romantic feelings for her, especially after growing insanely jealous of hers and Viktor's relationship. In a twist of irony, it was later Hermione herself who felt the same way when Ron started dating Lavender Brown in the sixth novel. This only worsened when she saw Lavender kiss Ron after the latter's first Quidditch game. When Hermione saw the two of them dating, she avoided Ron as much as possible and hung out with Harry instead. During the events of the sixth novel, Ron was jealous of her and Harry after they were invited to join Slug Club and he was not. After learning Hermione still has a friendship with Krum, Ron is still jealous of their relationship, especially after learning that Hermione kept contact with Krum for the past two years. However, after he was poisoned and sent to the hospital wing, Hermione came to visit him. While Ron was delirious, he called out Hermione's name instead of Lavender's in front of the girls' presence, causing lavender to run out of the room crying and effectively ending lavender and Ron's relationship and the two reconciled yet again.

Ron and Hermione's first kiss was in the Chamber of Secrets
They are said to have "sort of" dating by the time of The Deathly Hallows, as pointed out by Harry multiple times. During their stay at Grimmauld Place, Hermione and Ron lay next to each other where their hands found one another and played on the piano together. Later, when Ron temporarily abandons Hermione and Harry due to the influence of the Slytherin locket, Hermione is visibly distraught. When he returned, Hermione was visibly and understandably, upset with Ron for abandoning her and Harry. However, Ron and Hermione later reconciled when they were rescued from Malfoy Manor and recuperated at the Shell cottage. During the battle of Hogwarts, when they were in the Chamber of Secrets, Ron revealed his care for house elves and how he valued S.P.E.W. (her foundation to bring equal rights to the Elves), Hermione was overjoyed and they had their first kiss.
In the flash-forward that took place seventeen years into the future, Hermione and Ron have married and had two children together: a daughter named Rose and a son named Hugo.
Family
Parents
Hermione had a loving relationship to her parents, as her mother often called her "darling" or "sweetheart." Though she was unusal, Mr and Mrs Granger were proud of their daughter, and supported her when she found out she was a witch. However, they would not allow her to shrink her own teeth with magic.
During the Second Wizarding War, Hermione was very sadden to obliviate their memories of her, as she was seen nearly crying to have made that decision. She eventually found them in Australia and restored their memories.
Harry Potter

Best Friend/Brother-in-law; September 1991-present
Hermione and Harry first met on the Hogwarts Express, which they had initially been acquaintances. They eventually became friends when Hermione's life was saved by Ron and Harry from a Mountain Troll. She continued to support him in everything, including his Quidditch matches and his fight against Lord Voldemort. Though Harry valued his friendship with Hermione, he got annoyed with her consistent nagging him. Apart from this, the two best friends rarely fought each other. However, their relationship was restrained in the third novel, when Hermione turned in his Firebolt to McGonagall after the broom was sent by an anonymous source. Harry wouldn't talk to her for weeks until Hagrid reprimanded him and Ron for their inexcusable behavior towards Hermione. This made Harry realize that Hermione only did this just to protect him and they reconciled.
Many people had mistaken their relationship as romantic rather than platonic. Others such as Viktor Krum assumed they had romantic feelings for each other. However, Harry states they are just friends, even telling Ron that he thinks of Hermione as a sister. In turn, Hermione merely sees Harr as the brother she never had and has always been his older-sister figure.
Ginny Weasley

Best Friend/Sister-in-law; 1992-present
Ginny is one of Hermione's female best friends and someone she sees as a younger sister. They were only acquaintances throughout the first three novels: however when Hermione was staying over at the Weasley's house in the fourth boxer, Ginny and Hermione grew close with one another. The latter recognized Ginny’s feelings for Harry, and Hermione gave her advice on how to win his heart by showing interest in other boys and make him jealous. This plan would eventually work and lead Ginny and Harry to dating and later marrying each other. They also kept well hidden secrets between each other; Ginny was also the only one who Hermione told about being asked to the Yule Ball by Victor Krum and in the sixth novel, Hermione was the only one aware of Ginny practicing her flying for Quidditch.
They would eventually sisters-in-law when Hermione married Ginny's brother, Ron.
Arthur and Molly Weasley
Parents In law; 1992-Present
Arthur Weasley, was fascinated by Hermione's Muggle world and her background, even inviting Hermione’s parents for a drink when he first met them. When Lucius started insulting Hermione's parents in Chamber of Secrets Arthur got into a physical confrontation with Malfoy. He likely took offense to this insult to Hermione, who was like a second daughter for him and Molly.
However Molly coldly treated her when Rita Skeeter’s opinions came out about her supposedly breaking Harry's heart. However, they reconciled with each other Harry cleared up that he and Hermione never dated and that Rita wrote nothing but lies.
Fleur Delacour
Sister-in-law; 1994-Present
Fleur and Hermione initially did not get along in the books due to Hermione believing her to be uptight. During the sixth novel, Hermione did not like staying in the Burrow over the summer, growing tired of Fleur's somewhat stuck-up attitude.
Fred and George Weasley

Brothers-in-law; 1991-Present
Fred and George were extremely close with Hermione more than the other Weasley Brothers, and regarded her and Harry as younger siblings, often joking with them and being protective over her. This was extremely shown when they got angry at Draco for calling Hermione a “mudblood” and rushing to defend her at any second. Another part of their playful banter was when Hermione warned them that their Aging potion was not going tow ork against Dumbledore’s age line. Despite growing irritated by their antics, Hermione admired the twins for their cleverness and enjoyed pranks against Dolores Umbridge. She was deeply sadden by Fred’s death and even comforted Ginny through the ordeal. She became their sister-in-law when Hermione married Ron and become the aunt of George's children.
Other Relatives
Among other relatives of Hermione is her sister-in-law, Angelina Weasley (nee Johnson) and Audrey Weasley. However, Hermione was friends with Angelina in their Hogwarts years but her relationship with Audrey is unknown. She is the aunt of their children, Fred, Roxanne, Lucy and Molly.
Friends and Allies
Neville Longbottom

Despite their different personalities, both Hermione and Neville became close friends due to a love of knowledge.
Close Friends;
When the two first met at the beginning of the 1991-1992 school year, Hermione was the first to befriend Neville on the Hogwarts Express. She first showed him kindness by helping him find his toad, Trevor. During their time at school, Hermione defends Neville from bullies. By the time of their fourth year in Hogwarts, Hermione and Neville were close enough for her to notice how Neville was distress when "Alastor Moody" tortured a spider with one of the Unforgivable curses, even yelling at the professor to stop. Neville also asked with her money to go to the Yule doll. Although she was considering it she declined because she already had a date.
Hermione often fiercely defended Neville when others insulted him, and her friendship and support, as well as that of other D.A. members, likely contributed to Neville gradually gaining self-confidence and courage. Neville was fond of Hermione, and appreciative of her kindness and all the help she had given him. It was hinted that he spoke of her frequently to his grandmother, Augusta Longbottom, who seemed to already know a good deal about Hermione when they first met at Saint Mungo's in 1995. During the Battle of Hogwarts, Neville later saves Hermione (and Ron) from Nagini.
Luna Lovegood

close friend
Hermione and Luna met during their fifth and fourth years respectively.
Though Luna was quite odd in Hermione's eyes, she eventually accepted Luna despite her belief in creatures that exist without proof. After joining Dumbledore's Army, Hermione highly of Luna and even defended her when people insulted her, especially kicking Ron for teasing Luna about Gurdyroots. She even snapped at the portrait of Phineas Nigellus Black for calling her friend an oddity.
Luna comforted Hermione when she was upset over her fight with Ron. Hermione was also one of the five portraits Luna painted — along with Harry, Ron, Ginny, and Neville — and hung from her bedroom ceiling, the word "friends" linking them in gold writing
Acquaintances
Draco Malfoy

When they were younger, Hermione and Draco never got along
In their younger years, Draco and Hermione never got a long. She often got angry when he offended one of her friends, particlarly Harry and Ron. He coldy called her a "Filthy mudblood", which led some backlash from Hermione's friends, mainly Fred and George. In The Prisoner of Azkaban, Hermione slapped Draco in the face for his negative comments about her and Hagrid (in the film adaptation Hermione punches Draco in the face because he was the reason Buckbeak was sentenced to to death and for taking pleasure in his would-be execution. However, despite her hatred towards him, Hermione noticed Draco's health was declining during The Half-Blood Prince
However, by the time of The Cursed Child, Hermione and Draco are civil towards one another and work together to save Draco's son Scorpius and Hermione's nephew, Albus after they used an unauthorized time turner to travel through time. It is also revealed by Draco that he was always jealous of the deep bond Harry, Ron and Hermione had, seeing that he never had true friendships with Crabbe and Goyle.
Lavender Brown
At the start of their first year in Hogwarts, Hermione and Lavender were roommates but they never became close or good friends.
Tension between Hermione and Lavender began once the latter started dating her best friend Ron in 1996, because Hermione harbored romantic feelings for Ron. Lavender later broke up with Ron when he called out for Hermione's name instead of hers after he was poisoned by brandy that Slughorn unwittingly served him. Despite the breakup between Lavender and Ron Hermione chose to not display open affection towards Ron so Lavender's feelings would not get hurt. She also came to Lavender's rescue during the Battle of Hogwarts, blasting Fenrir Greyback away from her.[10] Unfortunately Lavender was mortally wounded by Greyback and was already dead by the time Hermione reached her. It can be assumed that Hermione was at least saddened by Lavenders death.
Parvati Patil
Hermione had a less tenacious relationship with Parvati but they weren't close.
Enemies
Rita Skeeter
During the fourth year, Rita Skeeter highly annoyed Hermione, putting gossip columns on her. She eventually found out about Rita's status as an unregistered Animagus and threatened to expose her. On the train ride in 1995, Hermione showed Ron and Harry that she had Rita trapped in her beetle form. Hermione later blackmailed Rita into writing a piece on the Dark Lord's return for the Quibbler, which was the paper owned by her friend Luna's father.
Lord Voldemort
Though Hermione and Voldemort hardly encounter each other on screen, Hermione was dedicated to destroying Voldemort's horcruxes so Harry could defeat her
Bellatrix Lestrange
Hermione hated the Death Eater Bellatrix Lestrange for her past deeds of torturing Neville's parents and killing her friend Sirius. Bellatrix tortured Hermione, due to her being a Muggle-born and carved "mudblood" on her arm. However, Hermione took the hairs of Bellatrix when they landed on her during interrogation and cyying out in agony. She used them to create apolyjuice potion whileẞ
It was shown that Hermione hated having to use her wand after stealing it from Malfoy Manor because of all the evil the wand did in the past, such as the torture of her friend Neville's parents and death of Sirius Black. However it was necessary evil to have Bellatrix's wand because she didn't really have her original wand. Hermione and Ginny all dueled Bellatrix.
Neutral
Severus Snape
In the films, Snape is less antagonistic towards Hermione.